ABSTRACT
Objective@#To understand the survival time and influencing factors of HIV/AIDS cases in Gansu province from 1997 to 2018.@*Methods@#A retrospective cohort study was conducted to analyze the AIDS epidemic data of Gansu from 1997 to 2018 collected from the National HIV/AIDS information system. Life-span table were used to calculate survival rate, Kaplan-Meier method was used to draw the survival curves and calculate the average survival time, the Cox proportional hazard regression model were used to analyze the risk factors for death for HIV/AIDS cases.@*Results@#Among 6 813 HIV/AIDS cases, 715 (10.5%) died, and the average survival time was 195.9 months (95%CI: 189.7-202.2). The survival rates of 12 months, 60 months, 120 months and 180 months were 91.5%, 86.1%, 79.9% and 73.8%, respectively. Cox proportional hazard regression model showed that the risk factors for death in the HIV/AIDS cases were age (≥51 years old vs. ≤25 years old, HR=1.906, 95%CI: 1.353-2.685), transmission route (blood borne and others transmission vs. heterosexual transmission, HR=1.593, 95%CI: 1.226-2.069), detection way (hospital admission detection, blood transfusion and preoperative examination vs. entry-exit health examination, pre-marital examination and physical examination of recruits, HR=5.113, 95%CI: 2.083-12.547), disease phase (AIDS phase vs. HIV infection phase: HR=4.012, 95%CI: 3.401-4.732), baseline CD4 count (no CD4 detected vs. CD4 count ≥350/μl, HR=5.446, 95%CI: 3.835-7.732), antiretroviral therapy (receiving no antiretroviral therapy vs. receiving antiretroviral therapy, HR=12.019, 95%CI: 9.861-14.648).@*Conclusions@#The average survival time of HIV/AIDS cases was above 16 years in Gansu during 1997 to 2018. Death risk of HIV/AIDS cases might be increased by age ≥51 years, hospital admission detection, blood transfusion and preoperative examination, AIDS phase of disease phase, no baseline CD4 detected and no receiving antiretroviral therapy. It is necessary to conduct early HIV test, diagnosis and antiretroviral treatment and increase antiretroviral treatment rates and CD4 testing rate to improve the survival of HIV/AIDS cases.
ABSTRACT
Objective To explore the situation of HIV infection among currently married MSM and the features of related sexual behavior on both males and females in Gansu province.Methods By "Place the recruitment" methodology,297 currently married MSM were recruited in Lanzhou and Tianshui cities of Gansu province.Participants filled in a questionnaire and underwent HIV antibody testing.SPSS 17.0 software was used to analyze the result and differences between positive HIV MSM and negative HIV MSM.Possible factors that influencing the HIV infection among currently married MSM were analyzed.Results Among those currently married MSM,the HIV positive rate was 4.7％.94.6％ participants admitted having had anal sex with male partners in the past 6 months while 30.9％ participants had more than 2 male sex partners in the past week,with the rate of condoms use as 45.9％.69.0％ of the participants had sex with females in the past 6 months,with the rate of condoms use as 24.9％.59.0％ of the participants did not use condoms when having sexual relations with parmers.Among HIV positive married MSM,the rate of AIDS awareness was 64.3％ and 7.1％ of them ever having had HIV testing last year and 92.9％ of them had anal sex with males.In the recent 6 months,14.3％ had ever used condom each time when having anal sex with males.35.7％ of the cases ever having had sex with females,with the rate of condom use as 60.0％.Conclusion HIV prevalence,low AIDS awareness,low HIV rate of testing and high rate of unprotected sex behavior with either sex partners were found among currently married MSM in Gansu province.Results of this study called for behavioral intervention and HIV testing measures should be taken immediately.